one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the cure of many myeloma. Its synthesis or review is critical for ensuring the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor within the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise sorts of most cancers, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their research is essential for optimizing the generation procedure and guaranteeing superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist used in the procedure of breast most cancers. Different intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain CAS NO. 155405-80-4 Acid (CAS NO. 949023-16-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in dealing with cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and compact cell lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have various applications, which includes antiviral Houses.
Vildagliptin Intermediates: Used in the creation of vildagliptin, an oral drug for FULVESTRANT INTERMEDIATES--6(N-2) form two diabetes that inhibits the enzyme DPP-four to control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication utilised to deal with kind two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).